Table 4.

Cox proportional hazards analysis involving all patients (N = 3095).

Variable	Hazard ratio	95% confidence interval	Chi-Square P
Age	1.05	(1.04-1.05)	< .0001
Male sex	1.05	(0.85-1.29)	0.66
Black race	2.56	(2.05-3.20)	< .0001
MTHFD1L A/A*	1.35	(1.00-1.82)	0.05
MTHFD1L A/G*	1.21	(0.97-1.52)	0.09

*Reference genotype G/G