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. 2011 Sep 23;11:266. doi: 10.1186/1471-2148-11-266

Table 2.

Fourteen of the most often positively selected residues of the Rubisco large subunit

Residue no1 Fitmode2 PAML3 Location of residues Residues within 9 Å4 Coevolving residue
no
Interactions
449 26 5 Helix G 374, 375, 376, 396, 399, 400, 401, 402, 407, 410, 411, 445, 446, 447, 448, 449,451, 452, 453, 454 128, 147 ID, SSU, DD
225 20 7 Helix 2 154, 155, 184, 187, 189, 219, 220, 221, 223, 224, 226, 227 None DD, SSU, ID
251 20 4 Helix 3 209, 210, 213, 217,247, 248, 249, 250, 252, 253 258, 261* DD, ID, SSU
145 16 7 Helix D 142**, 143, 144, 146, 147, 148, 149, 150, 281, 282, 314, 315, 316, 364, 365, 366 142**, 240 DD
142 14 4 Helix D 140,141, 143, 144, 145, 272, 276, 311, 312, 313, 314, 315, 364, 365 255**, 240 DD
95 13 4 23, 25, 26, 27, 54, 70, 71, 72, 73, 74, 93, 94, 96. 97. 98. 99 23, 86**, 326*, 332 SSU, ID
439 12 2 Helix G 413, 414, 417, 435, 436, 437, 438, 440, 441, 442, 443, 444, 446, 447 33*, 152, 151, 153, 135*, 281*, 310*, 440*, 470* ID
219 11 4 Helix 2 180, 181, 182, 184, 185, 186, 215, 216, 217, 218, 220, 221, 222, 223, 224, 225,227 121, 388, 423 DD, SSU, ID
279 11 1 Helix 4 143, 144, 152, 249, 253, 254, 274, 285, 286, 277, 278, 280, 281 301, 346 DD
328 11 3 Loop 6 319, 320, 321, 322, 323, 324, 326, 327, 329, 330, 332, 333, 462, 464 228*, 281* AS, ID
375 11 9 Strand 7 373, 374, 376, 377, 378, 379, 393, 396, 410, 411, 414, 436, 446, 449, 450, 453 395, 419* AS, ID, SSU
255 9 6 Helix 3 190, 228, 229, 230, 231, 248, 253, 254, 256, 257, 280, 281, 282, 283, 315, 316 101, 86**, 167, 149*, 169*, 256*, 320*, 371*, 398 SSU
28 8 9 N-terminus 26, 27, 29, 30, 76, 91, 94, 128, 129, 130, 131, 132 19, 355*, 93* SSU, ID
86 8 9 Strand C 33, 34, 35, 36, 37, 39, 41, 81, 84, 85, 87, 88 149*, 256*, 167, 169*, 222*, 317*, 320*, 371*, 398, 23, 30* DD

1 The residue number is according to the spinach Rubisco sequence (8RUC)

2 Number of groups with detected positively selected residues in Fitmodel

3 Number of groups with detected positively selected residues in PAML

4 *positively selected site; ** most often positively selected site; underlined residues are both within 9 Å and coevolve