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Fetoplacental Nrk is required for labor. A, labor phenotype in WT and Nrk-null dams mated to WT or Nrk-null male mice. Numbers of cases of normal (blue) and failed (red) labor are indicated. B, timing of delivery and number of offspring in recipient WT dams transplanted with WT or Nrk-null blastocysts. *, dams did not deliver offspring and were dissected at 22.75 dpc to examine fetuses in utero.
