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. 2011 Jun 29;286(33):28802–28810. doi: 10.1074/jbc.M111.258160

FIGURE 8.

FIGURE 8.

Nrk does not regulate the levels of progesterone and estrogen. A and B, the levels of progesterone (A) and estradiol (B) in the plasma of dams were measured at 17.5 and 19.5 dpc using LC-MS/MS. WT, WT dams with WT fetuses; Nrk-null, Nrk-null dams with Nrk-null fetuses. Each dot represents a single plasma sample. Numbers (n) of samples examined are indicated (top). p = 0.48 (A, 17.5 dpc), 0.16 (A, 19.5 dpc), 0.19 (B, 17.5 dpc), 0.47 (B, 19.5 dpc). C and D, the levels of progesterone (C) and estradiol (D) in control (XY or XXNrk) and Nrk-null (XNrkY or XNrkXNrk) placentas were measured at 19.5 dpc using ELISA. The mean ± S.D. values are shown. Numbers (n) of placentas examined are indicated. p = 0.33 (C) and 0.37 (D).