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. 2011 Jun 27;286(33):29325–29335. doi: 10.1074/jbc.M111.245092

FIGURE 4.

FIGURE 4.

Conserved basic residues on HEAT 11B/12B of CRM1. The conserved basic residues (Arg-553, Arg-556, Lys-590, Lys-594, Arg-596, and Arg-597) shown in dark blue lie at the end of the HEAT 11B/12B helices closest to the end of the C-terminal helix (as modeled by Dong et al. (9)). The NES binds on the opposite side of the CRM1 backbone at the A helices of these HEAT repeats.