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The distribution of H3K4 dimethylation differs between B cells versus plasma cells. A, the 11-kb IgH γ2a gene, is illustrated. The B cells and plasma cells were immunoprecipitated with antibodies to the H3K4 methylations as described above and subjected to qPCR analyses. B represents the data obtained with B cells, whereas C shows the data obtained in plasma cells. %IP, percentage immunoprecipitated.
