TABLE 1.
Simulation parameters for phospholipid vesicles
The bimolecular rate constant for the NO reaction with free deoxygenated hemoglobin is represented by kHb. Dex is the diffusion rate constant of NO in saline (in the extracellular space) and Din refers to the diffusion rate constants of both NO and hemoglobin inside a vesicle (in the intracellular space). Pm is the phospholipid membrane permeability of NO. The bottom row shows factors by which physiological parameter values were multiplied to test how this affects reaction kinetics. Bold indicates that heme concentrations given correspond to values below for D and hematocrit.
