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Amino acid sequence of MMP-2-cat (E108K/Q110V/E121A). Hyphens represent the identical residues between the catalytic domain of MMP-2 (MMP-2-cat) and MMP-2-cat (E108K/Q110V/E121A) (Mutant). The boldface letters in the sequence represent the active site residues of MMPs. FN × 3 represents the site of residues deleted to excise the fibronectin-like type II repeat region of MMP-2.
