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. 2011 Aug 4;286(38):33045–33052. doi: 10.1074/jbc.M111.281337

FIGURE 9.

FIGURE 9.

Summary of truncated Tg constructs and their secretory behavior. The schematic illustrates the results of secretion of distinct Tg truncation mutations presented in this study and in Ref. 28. From this we propose that folding the segment shown at bottom, including both linker and hinge regions, may be rate-limiting for Tg folding and export.