TABLE 1.
Pathological abnormalities of R26hAR transgenic mice
Genotype | Total number | Number of PIN | Number of adenocarcinoma |
---|---|---|---|
R26hARLoxP/WT:Osr1-Cre− | 14 | ||
<12Mo months | 10 | 0 | 0 |
>12 months | 4 | 0 | 0 |
R26hARLoxP/LoxP:Osr1-Cre− | 23 | ||
<12 months | 14 | 0 | 0 |
>12 months | 9 | 0 | 0 |
R26hARLoxP/WT:Osr1-Cre+ | 22 | 9 (40.9%) | 3 (13.6%) |
<12 months | 13 | 6 | 1 |
>12 months | 9 | 3 | 2 |
R26hARLoxP/LoxP:Osr1-Cre+ | 18 | 9 (50.0%) | 1 (5.6%) |
<12 months | 11 | 5 | 0 |
>12 months | 7 | 4 | 1 |