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. 2011 Jul 27;286(38):33641–33651. doi: 10.1074/jbc.M111.282509

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 2. — Voltage sensor-trapping activity of CssIV^E15A on A841N and L846A mutant channels. A and C, I-V plots in the absence of toxin; B and D, I-V plots in the presence of 500 nm CssIV^E15A with or without a prepulse. A, WT rNa_v1.2a (open circles) and A841N (open squares). B, A841N, in the absence (open squares, −Pre) and presence (filled squares, +Pre) of the prepulse. C, WT rNa_v1.2a (open circles) and L846A (open triangles). D, L846A in the absence (open triangles, −Pre) and presence (filled triangles, +Pre) of the prepulse.