TABLE 1.
Numbers of occupied mouse DR5 RAREs in the initial list (15,925 predicted sites), the list of conserved 181 sites located ±10 kb from TSSs, and in the final list of 138 RAREs
For finding significant occupied sites, a cutoff p value of 0,00001 was applied. As a control, the same strategy was applied to a random list of 15,925 sequences of 17 kb.
| F9 cells | RAREs |
|||
|---|---|---|---|---|
| Random list | Predicted (159,25) | Conserved (181) | Final list (138) | |
| Untreated | 32 (0.2%) | 691 (4%) | 48 (26%) | 39 (28%) |
| RA 2 h | 62 | 1,109 | 49 | 45 |
| RA 24 h | 39 | 964 | 46 | 33 |
| RA 48 h | 85 | 1,523 (9%) | 71 | 55 |
| Total | 112 | 1,791 (11%) | 76 (42%) | 58 (42%) |