Skip to main content
. Author manuscript; available in PMC: 2011 Oct 11.
Published in final edited form as: J Immunol. 2010 Mar 29;184(9):5085–5093. doi: 10.4049/jimmunol.0902710

FIGURE 1.

FIGURE 1

E. muris infection inhibits the production of splenic, Ag-specific IgG-secreting cells. E. muris OMP-19–specific IgM and IgG (A), and day 28 postinfection isotype-switched IgG (B), were measured in the serum of C57BL/6 mice by ELISA. C, The frequencies and numbers of Ag-specific IgM-secreting (●) and IgG-secreting (■) cells in the spleen (top panels) and lymph nodes (bottom panels) were determined by ELI-SPOT analysis. Spots produced by cells from mock-infected control mice, which were negligible, were subtracted from the number of spots obtained from the infected mice. The data are representative of three independent experiments in which three mice were analyzed at each time point.

HHS Vulnerability Disclosure