TABLE 3.
Effect of ischemia on activity of electron transport chain complexes
Activities are expressed in nmol/min/mg, except for complex IV in 1/min/mg. Results are mean ± S.E., n = 6 for each group, except n = 4 for complex IV data.
| Enzymatic activity |
||||
|---|---|---|---|---|
| WT |
MLS-STAT3E |
|||
| TC | Ischemia | TC | Ischemia | |
| Complex I | 937 ± 56 | 669 ± 48a | 750 ± 45b | 649 ± 36 |
| NFR | 1904 ± 58 | 1749 ± 76 | 2103 ± 120 | 1897 ± 68 |
| Complex II | 248 ± 9 | 238 ± 16 | 197 ± 15b | 200 ± 11 |
| Complex III | 8471 ± 274 | 8500 ± 99 | 8392 ± 410 | 8167 ± 333 |
| Complex IV | 414 ± 16 | 299 ± 28a | 401 ± 21 | 291 ± 21a |
| CS | 2770 ± 41 | 2679 ± 47 | 2691 ± 162 | 2821 ± 62 |
a p < 0.05 Ischemia versus corresponding TC.
b p < 0.05 MLS-STAT3E versus corresponding WT.