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. 2011 Jul 1;286(34):29734–29747. doi: 10.1074/jbc.M111.220939

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — IQGAP1 is overexpressed in HER2(+) breast cancer. A and B, IQGAP1 protein expression was evaluated by immunohistochemistry in normal breast specimens (Nl, upper panels) and HER2(+) (3+ by immunohistochemistry and/or amplified by FISH) invasive breast carcinomas (Ca, lower panels). Representative images are shown. The final magnification is 100× (A) and 400× (B). H&E, hematoxylin and eosin. C, IQGAP1 protein expression was evaluated by immunohistochemistry in hormone receptor-positive (HR(+); upper panel) and triple-negative (TNBC; lower panel) invasive breast carcinomas. Representative images are shown. The final magnification is 100×.