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. 2011 Jun 24;286(34):30022–30033. doi: 10.1074/jbc.M111.261206

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 2. — Total HexCer and long chain base levels in 4-month-old mice. Total GalCer (A), OH-HexCer (B), and GlcCer (C) levels and acyl chain distribution are shown. The left-hand columns show total HexCer levels, and the other columns show levels of individual acyl chains. Values are means ± S.D. for which duplicate analyses were performed (n = 2). *, p < 0.01. D, -fold change in CerS2-null versus WT mice for the long chain bases sphingosine (So), sphinganine (Sa), and sphingosine 1-phosphate (S1P) at different ages: newborn (P0), 2 months (2M) of age, and 4 months (4M) of age. Values are means ± S.D. (n = 2). *, p < 0.05; **, p < 0.01.