Fig. 6.

Typical recording of arterial blood pressure (ABP) response to arterial injection of α,β-me-ATP; 0.125 mM of α,β-me-ATP were injected. Arrows indicate a start of injections. Top: effects of NGF infusion on pressor response to stimulation of P2X. α,β-me-ATP was injected into arterial blood supply of the muscles of saline control and experimental legs infused with NGF (0.25 μg/h for 72 h) in healthy rats. Bottom: effects of NGF neutralization on the pressor response to stimulation of P2X in sham control leg and occluded leg. NGF-Ab (10 μg each leg) was injected into both legs 24 h before experiments. Then, α,β-me-ATP was arterially injected to examine the pressor response to stimulation of P2X.