Table 1.
Mortality, % |
|||||
---|---|---|---|---|---|
Surgical Procedure | Animal No. | Surgical Death | Single procedure | Accumulative | |
Control | Sham operate | 13 | 0 | 0 | |
Ab | Aortic banding | 86 | 17 | 20 | |
Ab + DeAb | Debanding after Ab | 11 | 2 | 18 | 34 |
I/R-2m | Ischemia-reperfusion | 14 | 3 | 21 | |
MI-2m | LAD permanent ligation | 18 | 7 | 39 | |
Ab + I/R | I/R on Ab rats | 45 | 14 | 31 | 45 |
Ab + I/R + DeAb | DeAb on Ab + I/R rats | 19 | 6 | 32 | 62 |
MI, myocardial infarction; LAD, left anterior descending artery. Calculation for accumulative mortality of multiprocedures is as follows: Ab + DeAb, (11/0.8 − 11 × 0.82)/(11/0.8) × 100 = 34%; Ab + I/R, (45/0.8–45 × 0.69)/(45/0.8) × 100 = 45%; and Ab + I/R + DeAb, (19/0.69/0.8 − 19 × 0.68)/(19/0.69/0.8) × 100 = 62%.