Table 3.

Cardiac morphology by direct imaging

	Control	Ab-4m	Ab + DeAb	I/R-2m	MI-2m	Ab + I/R	Ab + I/R + DeAb
n	8	8	9	9	11	11	11
MI, % LV area	0 ± 0	0 ± 0	0 ± 0	15 ± 1.3**	21 ± 0.9**#	15 ± 1.3**	13 ± 1.2**
AO, mm2	4.4 ± 0.3	5.0 ± 0.3	4.9 ± 0.4	4.6 ± 0.2	4.9 ± 0.3	5.3 ± 0.3	6.1 ± 0.3
Ab, mm2	4.4 ± 0.3	1.4 ± 0.2**	2.8 ± 0.3**∧∧	4.6 ± 0.3	4.9 ± 0.3	1.3 ± 0.1**	3.5 ± 0.2**∧∧
Ab-to-AO ratio	1.00 ± 0	0.28 ± 0.01**	0.54 ± 0.02**∧∧	1.00 ± 0	1.00 ± 0	0.25 ± 0.01**	0.58 ± 0.02**∧∧
LV, g	1.1 ± 0.1	1.8 ± 0.1**	1.2 ± 0.1∧∧	1.2 ± 0.1	1.2 ± 0.1	1.8 ± 0.1**	1.4 ± 0.1*∧
Body wt, g	542 ± 48	609 ± 16	550 ± 14	541 ± 24	530 ± 13	578 ± 22	605 ± 29
LV-to-body wt ratio	2.0 ± 0.1	3.0 ± 0.1**	2.2 ± 0.1∧∧	2.2 ± 0.1	2.2 ± 0.2	3.1 ± 0.2**	2.4 ± 0.1∧∧

Values are means ± SE; n, no. of rats. AO, normal aortic cross-sectional area; Ab, banded aortic cross-sectional area.

^*P < 0.05 and

^**P < 0.01 compared with control.

^#P < 0.05 compared with I/R-2m, Ab + I/R, and Ab + I/R + DeAb.

^∧P < 0.05 and

^∧∧P < 0.01 compared with Ab-4m.