Table 3.
Associations between PBDEs and TH in second trimester pregnant women in Northern and Central California
| Free T4 (N=25)
|
Total T4 (N=24)
|
TSH (N=25)
|
||||
|---|---|---|---|---|---|---|
| β | 95% CI | β | 95% CI | β | 95% CI | |
| PBDE groupings (ng/mL) | ||||||
| ΣPBDE5 | −0.02 | −0.15, 0.12 | 0.50 | −1.04, 2.04 | 0.40 | −0.07, 0.87# |
| Individual congeners (ng/mL) | ||||||
| BDE-28 | −0.11 | −0.24, 0.02# | −0.57 | −2.12, 0.98 | 0.38 | −0.12, 0.87 |
| BDE-47 | −0.04 | −0.16, 0.09 | 0.02 | −1.37, 1.41 | 0.39 | −0.04, 0.82# |
| BDE-85 | −0.01 | −0.10, 0.08 | 0.55 | −0.47, 1.57 | 0.33 | 0.02, 0.64* |
| BDE-99 | 0.01 | −0.09, 0.11 | 0.84 | −0.31, 1.99 | 0.24 | −0.12, 0.60 |
| BDE-100 | −0.02 | −0.12, 0.07 | 0.21 | −1.02, 1.43 | 0.23 | −0.12, 0.59 |
| BDE-153 | 0.04 | −0.06, 0.14 | 0.66 | −0.66, 1.98 | 0.07 | −0.32, 0.45 |
| BDE-207 | 0.06 | −0.07, 0.19 | 0.51 | −0.96, 1.97 | −0.72 | −1.10, −0.34** |
p < 0.05;
p < 0.01;
p < 0.10
Adjusted for lipid content and insurance type; and total T4 models are additionally adjusted for age.