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. 2011 Oct 11;6(10):e25546. doi: 10.1371/journal.pone.0025546

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Miao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The group means were significantly different in: (D_outer/D_all)_old>(D_outer/D_all)_AD (one-way ANOVA test, p<0.05) .The horizontal line indicates a cutoff point of 0.647 by ROC analysis where13 of 16 elderly subjects and 13 of 15 AD patients are correctly categorized.