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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Clin Genet. 2011 Jul 18;80(5):407–414. doi: 10.1111/j.1399-0004.2011.01739.x

Table 2.

Lifetime risk estimates (through age 85) for first-degree relatives of people with AD, stratified by gender, APOE genotype, and ethnic group

Genotype White Men White Women AA Men AA Women
ε2/ε3 13% 19% 33% 36%
ε3/ε3 18% 29% 41% 49%
ε2/ε4 25% 49% 48% 69%
ε3/ε4 29% 52% 56% 73%
ε4/ε4 56% 57% 77% 74%

Note: AA = African American. ε2/ε2 estimates are not provided because there was not sufficient population prevalence of this genotype in our epidemiological studies to provide robust risk estimates