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Metabolism of arachidonic acid into specific prostanoids. COX-1= cyclooxygenase 1; COX-2 = cyclooxygenase 2; PGIS = prostacyclin synthase; TXS = thromboxane synthase; cPGES = cytosolic prostaglandin E synthase; mPGES-1 = microsomal prostaglandin E synthase 1; mPGES-2 = microsomal prostaglandin E synthase 2; PGDS = prostaglandin D synthase; PGFS = prostaglandin F synthase.
