Table 2.
Total N=82 |
50% N=28 |
65% N=29 |
80% N=25 |
P-value | |
---|---|---|---|---|---|
Final 6 hour IV insulin dose (units) | 14.2 (11.5) | 17.0 (17) | 12.7 (7.4) | 12.8 (7.6) | 0.28 |
Initial Detemir dose (units) | 35 (18) | 33 (19) | 32 (13) | 41 (21) | 0.17 |
24 hour total insulin (units) | 66 (27) | 66 (34) | 61 (18) | 71 (27) | 0.42 |
24 hour carbohydrate intake (grams) | 128 (77) | 119 (78) | 122 (70) | 144 (84) | 0.48 |
Reversion to insulin infusion (%) | 3 (4%) | 2 (7%) | 0 | 1 (4%) | NA |
% basal insulin overall | 0.68 (0.15) | 0.67 (0.16) | 0.68 (0.15) | 0.70 (0.15) | 0.76 |
Morning glucose | |||||
Day 1 Mean (mg/dl) | 139 (47) | 144 (48) | 141 (51) | 130 (31) | 0.49 |
% at target (80–130 mg/dl) | 42 (51%) | 10 (36%) | 18 (63%) | 14 (56%) | 0.12 |
3-Day Mean (mg/dl) | 110 (20) | 105 (30) | 112 (24) | 0.72 | |
% at target (80–130 mg/dl) | 53 (65%) | 18 (64%) | 20 (69%) | 15 (60%) | 0.79 |
Total glucose | |||||
Day 1 Mean (mg/dl) | 154 (44) | 154 (49) | 156 (45) | 150 (40) | 0.89 |
% at target (80–180 mg/dl) | 60 (73%) | 21 (75%) | 20 (69%) | 19 (76%) | 0.70 |
3-day Mean (mg/dl) | 138 (31) | 142 (36) | 135 (29) | 138 (29) | 0.70 |
% at target (80–180 mg/dl) | 74 (90%) | 24 (86%) | 27 (93%) | 23 (92%) | 0.60 |
Hypoglycemia* | |||||
Day 1 | 2 (2.4%) | 0 | 1 (3.5%) | 2 (8%) | NA |
Overall | 9 (11%) | 0 | 6 (21%) | 3 (12%) | 0.02 |
<40 mg/dl Overall | 1 (1.2%) | 0 | 0 | 1 (4%) | NA |
Data are presented as mean (standard deviation) or number (%).
The 65 and 80% groups are collapsed and compared to the 50% group using Fisher’s exact test for the race variable due to insufficient cell counts.