Table 2.

Mechanical properties of bone from 12-week-old WT and YF mice

	WT	YF
Peak moment (Nmm)	32.30 ± 1.23	38.24 ± 2.75*
Yield moment (Nmm)	28.78 ± 1.41	31.49 ± 2.70
Stiffness (Nmm2)	1222 ± 74.1	1209 ± 124.4
Yield displacement (mm/mm2)	0.02 ± 0.001	0.05 ± 0.01*
Postyield displacement (mm/mm2)	0.004 ± 0.001	0.002 ± 0.002
Work to failure (Nmm*mm/mm2)	0.61 ± 0.07	0.76 ± 0.16
Work to failure postyield (Nmm*mm/mm2)	0.18 ± 0.04	0.22 ± 0.08

Femora were placed on the prongs of a materials testing machine. A constant load of 0.05 mm/s was applied to femora until bone failure, during which displacement and force were collected at 100 Hz. Force and displacement values were normalized using terms as described in Materials and Methods. Whole-bone mechanical properties were determined from the moment vs. normalized displacement curves. n = 10 mice/genotype. Mean ± SEM

* P < 0.05 compared to WT