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. Author manuscript; available in PMC: 2011 Oct 12.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Oct 7;(4):CD006690. doi: 10.1002/14651858.CD006690.pub2
Outcome or Subgroup Studies Participants Statistical Method Effect Estimate
1.1 Normalisation of fasting blood
glucose at trial completion (n)
8 625 Risk Ratio ( IV , Random , 95% CI ) 2.07 [1.52, 2.82]
 1.1.1 Jiantang Bushen decoction 1 45 Risk Ratio ( IV , Random , 95% CI ) 1.72 [1.04, 2.86]
 1.1.2 Xiaoke Huaya tablet 1 168 Risk Ratio ( IV , Random , 95% CI ) 2.54 [1.70, 3.79]
 1.1.3 Qimai Jiangtang Yin
decoction
1 64 Risk Ratio ( IV , Random , 95% CI ) 2.89 [1.41, 5.90]
 1.1.4 Jian Pi Zhi Shen Huo Xue 1 77 Risk Ratio ( IV , Random , 95% CI ) 1.92 [1.28, 2.90]
 1.1.5 Tang Kang Yin 1 76 Risk Ratio ( IV , Random , 95% CI ) 3.75 [1.74, 8.09]
 1.1.6 Xiaoke Yuye decoction 1 65 Risk Ratio ( IV , Random , 95% CI ) 1.89 [1.14, 3.14]
 1.1.7 Tang Heng I 1 42 Risk Ratio ( IV , Random , 95% CI ) 5.00 [1.26, 19.87]
 1.1.8 Jinqi jiangtang 1 88 Risk Ratio ( IV , Random , 95% CI ) 1.17 [0.90, 1.53]
1.2 Incidence of diabetes (n) 8 632 Risk Ratio ( M-H , Random , 95% CI
)
0.33 [0.19, 0.58]
 1.2.1 Jiangtang Bushen tang 1 45 Risk Ratio ( M-H , Random , 95% CI
)
0.32 [0.04, 2.84]
 1.2.2 Xiaoke Huayu Pian 1 168 Risk Ratio ( M-H , Random , 95% CI
)
.36 [0.10, 1.30]
 1.2.3 Qimai Jiangtang Yin 1 64 Risk Ratio ( M-H , Random , 95% CI
)
0.18 [0.02, 1.39]
 1.2.4 Tang King Yin 1 76 Risk Ratio ( M-H , Random , 95% CI
)
0.06 [0.01, 0.46]
 1.2.5 Jian pi zhi shen huo xue 1 77 Risk Ratio ( M-H , Random , 95% CI
)
0.59 [0.19, 1.84]
 1.2.6 Jinqi Jiangtang tablet 1 88 Risk Ratio ( M-H , Random , 95% CI
)
0.61 [0.11, 3.47]
 1.2.7 Xiaoke Yuye 1 72 Risk Ratio ( M-H , Random , 95% CI
)
0.33 [0.07, 1.54]
 1.2.8 Tangheng I Plus 1 42 Risk Ratio ( M-H , Random , 95% CI
)
0.18 [0.02, 1.43]
1.3 Fasting blood glucose (mmol/L) 9 742 Mean Difference ( IV , Random ,
95% CI )
−0.41 [−0.66, −0.16]
 1.3.1 Jiangtang Bushen decoction 1 45 Mean Difference ( IV , Random ,
95% CI )
 0.15 [ 0.42, 0.12]
 1.3.2 Xiaoke Huayu tablet 1 168 Mean Difference ( IV , Random ,
95% CI )
−1.40 [−1.72, −1.08]
 1.3.3 Qimai Jiangtang Yin formula 1 64 Mean Difference ( IV , Random ,
95% CI )
−0.03 [−0.32, 0.26]
 1.3.4 Jinqi Jiangtang tablet 1 88 Mean Difference ( IV , Random ,
95% CI )
−0.58 [−0.74, −0.42]
 1.3.5 Jian Pi Zhi Shen Huo Xue 1 76 Mean Difference ( IV , Random ,
95% CI )
−0.09 [−0.35, 0.17]
 1.3.6 Xiaoke Yuye decoction 1 72 Mean Difference ( IV , Random ,
95% CI )
−0.39 [−0.99, 0.21]
 1.3.7 Tang Kang Yin decoction 1 76 Mean Difference ( IV , Random ,
95% CI )
−0.21 [−0.33, −0.09]
 1.3.8 Tang Heng I decoction 1 42 Mean Difference ( IV , Random ,
95% CI )
−1.24 [−2.53, 0.05]
 1.3.9 Liu Wei Di Huang capsule 1 111 Mean Difference ( IV , Random ,
95% CI )
−0.31 [−0.58, −0.04]
1.4 2hr fasting blood glucose
(mmol/L) [ after oral glucose
tolerance test]
9 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.1 Jiangtang Bushen decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.2 Xiaoke Huaye tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.3 Qimai Jiangtang Yin
decoction
1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.4 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.5 Jian Pi Zhi Shen Huo Xue 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.6 Xiaoke Yuye decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.7 Tang Kang Yin decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.8 Tang Heng I decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.4.9 Liu Wei Di Huang capsule 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.5 HbA1c (%) 3 317 Mean Difference ( IV , Random ,
95% CI )
−0.47 [−1.00, 0.06]
 1.5.1 Xiaoke Huayu tablet 1 168 Mean Difference ( IV , Random ,
95% CI )
−0.63 [−0.99, −0.27]
 1.5.2 Jian Pi Zhi Shen Huo Xue 1 77 Mean Difference ( IV , Random ,
95% CI )
−0.87 [−1.43, −0.31]
 1.5.3 Xiaoke Yuye decoction 1 72 Mean Difference ( IV , Random ,
95% CI )
−0.06 [−0.12, 0.00]
1.6 Insulin (μU/ml) 6 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.6.1 Jiangtang Bushen decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.6.2 Qimai Jiangtang Yin
decoction
1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.6.3 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.6.4 Jian Pi Zhi Shen Huo Xue 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.6.5 Tang Kang Yin decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.6.6 Tang Heng I decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.7 IAI (insulin sensitivity) 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.7.1 Qimai Jiangtang Yin
decoction
1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.8 Total cholesterol (mmol/L) 7 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.1 Jiangtang Bushen tang 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.2 Xiaoke Huayu Pian 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.3 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.4 Jian Pi Zhi Shen Huo Xue 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.5 Xiaoke Yuye 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.6 Tang Kang Yin 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.8.7 Liu Wei Di Huang capsule 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.9 Lipids: HDL (mmol/L) 2 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.9.1 Jian Pi Zhi Shen Huo Xue 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.9.2 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.10 Trigylcerides (mmol/L) 7 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.1 Jiangtang Bushen tang 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.2 Xiaoke Huayu Pian 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.3 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.4 Jian Pi Zhi Shen Huo Xue 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.5 Xiaoke Yuye decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.6 Tang Kang Yin decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.10.7 Liu Wei Di Huang Wan 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.11 Body Mass Index (kg/m2) 6 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.11.1 Jiangtang Bushen 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.11.2 Jian Pi Zhi Shen Huo Xue 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.11.3 Xiaoke Yuye decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.11.4 Tang Kang Yin decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.11.5 Liu Wei Di Huang capsule 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.11.6 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.12 Diastolic blood pressure
(mmHg)
2 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.12.1 Liu wei di huang wan 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.12.2 Jinqi jiangtang tablets 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.13 Systolic Blood Pressure
(mmHg)
2 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.13.1 Liu wei di huang wan 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.13.2 Jinqi jiangtang tablets 1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.14 Main ingredient Astragalus
membranecus (≥30g): Fasting blood
glucose (mmol/ml)
4 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.14.1 Jinqi Jiangtang tablet 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.14.2 Xiaoke Yuye decoction 1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.14.3 Shan yao, shan zha, huang
qi etc
1 Mean Difference ( IV , Random ,
95% CI )
No totals
 1.14.4 Qimai Jiangtang Yin
formula
1 Mean Difference ( IV , Random ,
95% CI )
No totals
1.15 Hypoglycaemic effects of
herbal medicines with lifestyle
modification compared lifestyle
modification alone
9 Other data No numeric data