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The antinociceptive effect of recombinant soluble TNF receptor on the mechanical threshold in rats treated with ddC. At 2 weeks after ddC, rats received intrathecal injection of recombinant soluble TNF receptor or vehicle. Administration of siRNA of TNFα, but not vehicle reversed the mechanical threshold, F(1,14)=25.923, p < 0.001 vs vehicle, n=8, General Linear Model, repeated measure, SPSS.
