Table 2.
Explanatory variables | General population, patients with type 1 and 2 diabetes (n=4213) |
|
Filaggrin null mutation | ||
Percentage (n/ntotal) | Adjusted OR* with 95% CI | |
Sex | ||
Men | 7.8 (159/2029) | 1 (reference) |
Women | 8.8 (193/2184) | 1.18 (0.94 to 1.47) |
Group | ||
Non-diabetic | 7.8 (246/3136) | 1 (reference) |
Screen-detected diabetes | 9.1 (6/66) | 1.23 (0.52 to 2.88) |
Self-reported diabetes | 12.8 (17/133) | 1.78 (1.05 to 3.04)‡, p=0.032 |
Type 1 diabetes | 6.7 (7/104) | 0.86 (0.39 to 1.87) |
Type 2 diabetes | 9.8 (76/774) | 1.37 (1.003 to 1.89)‡, p=0.048 |
General population and patients with type 2 diabetes (n=4109) |
||
Explanatory variables | Diabetes† |
|
Percentage (n/ntotal) | Adjusted OR* with 95% CI | |
Sex | ||
Men | 29.8 (586/1967) | 1 (reference) |
Women | 18.1 (387/2142) | 0.56 (0.46 to 0.67)‡, p=0.001 |
Filaggrin | ||
Wild type | 23.2 (874/3764) | 1 (reference) |
Null mutation | 28.2 (99/345) | 1.50 (1.10 to 2.06)‡, p=0.011 |
BMI (kg/m2) | ||
<25 | 9.7 (167/1713) | 1 (reference) |
25–30 | 23.2 (341/1469) | 1.97 (1.56 to 2.47)‡, p=0.001 |
>30 | 49.1 (461/905) | 7.36 (5.79 to 9.36)‡, p=0.001 |
Non-diabetic, healthy controls from the general population in Copenhagen; Screen-detected diabetes, diabetes screening group defined as subjects who did not report diabetes but who had a fasting blood glucose ≥7 and/or glycated haemoglobin ≥6.5%. Self-reported diabetes, diabetes group defined as subjects who gave an affirmative answer to the question: ‘Have you ever been told that you suffered from diabetes?’
Mutually adjusted for variables shown in the table and age.
Diabetes was defined as belonging to the ‘screen-detected diabetes group,’ the ‘self-reported diabetes group,’ or the ‘type 2 diabetes group.’ The ‘type 1 diabetes groups’ was regarded as missing data.
Statistically significant.