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. 2011 Apr 27;1:2. doi: 10.1186/2045-9912-1-2

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Copyright ©2011 Haelewyn et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of NBO on MCAO-induced brain damage and behavioral motor deficits. (A) NBO-treated rats (n = 9) had greater total and striatal damage, and showed a trend toward an increase in cortical brain damage, as compared with MCAO control rats treated with medical air (n = 10). Sham animals showed no brain damage (n = 6; data not shown). (B) NBO further increased brain edema and swelling as compared to MCAO control rats treated with medical air. (C) Typical examples of brain slices in MCAO rats treated with either medical air or NBO. Data are expressed as mean ± SEM (mm³). * P < 0.01 vs MCAO control rats treated with medical air.