Table 3.
Intervention | Control | Multivariate linear regression coefficients (95%CI) | ||
---|---|---|---|---|
Diastolic blood pressure | Systolic blood pressure | |||
N | 288 | 4789 | ||
Mean age (years) (SD) | 63.3 (12.4) | 65.3 (11.2) | -0.13 (-0.15, -0.11) | 0.12 (0.08, 0.16) |
Males (n (%)) | 155 (53.8%) | 2532 (52.9%) | 0.26 (-0.26, 0.79) | -0.12 (-1.02, 0.78) |
Smoking status | ||||
Never smoker | 119 (41.3%) | 1963 (41.0%) | 1.0 | 1.0 |
Ex-smoker | 99 (34.4%) | 2256 (47.1% | -0.55 (-1.11, 0.006) | -0.07 (-1.03, 0.89) |
Current smoker | 34 (11.8%) | 570 (11.9%) | -1.36 (-2.20, -0.51) | 0 (-1.44, 1.44) |
Unknown | 36 (12.5%) | - | ||
Length of follow-up (days) | ||||
Mean (SD) | 321.6 (143.4) | 325.7 (139.5) | -0.0006 (-0.002, 0.001) | 0.001 (-0.002, 0.004) |
Median (IQR) | 321 (184, 445.5) | 338 (198, 440) | ||
Baseline diastolic blood pressure (mmHg) Mean (SD) | 8.2 (1.8) | 7.7 (1.5) | 0.38 (0.36, 0.41) | - |
Sub-groups (n (%)) | ||||
< 80 mmHg | 145 (50.3%) | 2645 (55.2%) | ||
80-89 mmHg | 107 (37.2%) | 1688 (35.2%) | ||
90-99 mmHg | 24(8.3%) | 385 (8.0%) | ||
> 100 mmHg | 12 (4.2%) | 71 (1.5%) | ||
Baseline systolic blood pressure (mmHg) Mean (SD) | 139.6 (18.0) | 138.3 (14.6) | - | 0.39 (0.36, 0.42) |
Sub-groups (n (%)) | ||||
< 120 mmHg | 27 (9.4%) | 341 (7.1%) | ||
120-129 mmHg | 48 (16.7%) | 755 (15.8%) | ||
130-139 mmHg | 80 (27.8%) | 1346 (28.1%) | ||
140-149 mmHg | 71 (24.7%) | 1389(29.0%) | ||
> 150 mmHg | 62 (21.5%) | 958 (20.0%) | ||
Final value (mean) (SD) (mmHg) | ||||
Diastolic blood pressure | 75.2 (9.3) | 76.1 (10.2) | ||
Systolic blood pressure | 134.6 (15.9) | 137.6 (16.8) | ||
Mean change (SD) (mmHg) | ||||
Diastolic blood pressure | -3.3 (11.7) | -0.6 (10.8) | ||
Systolic blood pressure | -5.0 (19.0) | -0.7 (17.8) | ||
Difference in final values (mmHg) | ||||
(intervention - control) (95% CI) | ||||
Diastolic blood pressure | -0.9 (-2.1, 0.3) | |||
Systolic blood pressure | -3.0 (-5.0, -1.0) | |||
Adjusted mean difference in final blood pressure between intervention and control* (mmHg) (95%CI) |
-1.6 (-2.7, -0.4) | -3.5 (-5.5, -1.5) | ||
Adjusted mean difference in final blood pressure between intervention and control by sub-group of baseline values (95%CI) (mmHg) |
< 80 mmHg -1.0 (-2.6, 0.6) 80-89 mmHg -1.6 (-3.5, 0.3) 90-99 mmHg -3.1 (-7.7, 1.5) ≥ 100 mmHg -0.1 (-8.4, 8.2) |
< 120 mmHg -1.9 (-8.1, 4.4) 120-129 mmHg -2.7 (-7.4, 1.9) 130-139 mmHg -1.6 (-5.2, 2.0) 140-149 mmHg -4.6 (-8.5, -0.8) ≥ 150 mmHg -5.4 (-10.4, -0.4) |
* adjusted for age, sex, baseline values, smoking status, length of follow-up