Table 4.
Intervention | Control | Multivariate linear regression coefficients (95%CI) |
|
---|---|---|---|
N | 239 | 1961 | |
Mean age (years) (SD) | 63.1 (11.7) | 64.4 (10.9) | -0.001 (-0.005, 0.002) |
Males (n (%)) | 129 (54.0) | 1024 (52.2) | -0.15 (-0.22, -0.08) |
Smoking status | |||
Never smoker | 87 (36.4%) | 824 (42.0) | 1.0 |
Ex-smoker | 92 (38.5%) | 906 (46.2) | -0.03 (-0.11, 0.04) |
Current smoker | 29 (12.1% | 231 (11.8) | 0.01 (-0.10, 0.12) |
Unknown | 31 (13.0%) | - | |
Length of follow-up (days) | |||
Mean (SD) | 322.7 (134.4) | 330.4 (122.9) | -0.0001 (-0.0004, 0.0002) |
Median (IQR) | 313 (215, 419) | 343 (235, 405) | |
Baseline serum cholesterol (mmol/l) Mean (SD) | 4.3 (1.0) | 4.4 (1.0) | 0.60 (0.56, 0.63) |
Sub-groups (n (%)) | |||
< 4 mmol/l | 88 (36.8%) | 656 (33.5%) | |
4.0-4.9 mmol/l | 82 (34.3%) | 787 (40.1%) | |
5.0-5.9 mmol/l | 46 (19.2%) | 310 (15.8%) | |
6.0-6.9 mmol/l | 9 (3.8%) | 75 (3.8%) | |
> 7.0 mmol/l | 3 (1.3%) | 33 (1.7%) | |
Final serum cholesterol (mmol/l) (mean) (SD) | 4.1 (1.1) | 4.3 (1.0) | |
Mean change in serum cholesterol (mmol/l) (SD) | -0.2 (1.0) | -0.1 (0.9) | |
Difference in final serum cholesterol (intervention - control) (95% CI) | -0.2 (-0.3, -0.0) | ||
Adjusted mean difference in final serum cholesterol between intervention and control (mmol/l)(95%CI)* | -0.1 (-0.2, -0.1) | ||
Adjusted mean difference in final serum cholesterol between intervention and control by sub-group of baseline values (mmol/l) (95%CI) | |||
< 4 mmol/l | 0.0 (-0.2, 0.2) | ||
4.0-4.9 mmol/l | -0.3 (-0.5, -0.1) | ||
5.0-5.9 mmol/l | -0.0 (-0.3, -0.3) | ||
6.0-6.9 mmol/l | -0.1 (-0.9, 0.7) | ||
> 7.0 mmol/l | -0.7 (-2.6, 1.2) |
* adjusted for age, sex, baseline values, smoking status, length of follow-up