Fig. 7.

H4IIEC3 cells were transfected with the reporter plasmid and PPAR-α or -γ as labeled. Dominant negative (α1-DN) AMPK was transfected at the same time as the reporter and expression plasmids. Concentrations of WY, rosiglitazone, and AM580 were as described in Figs. 1–3, and treatments were for 24 h. A: PPAR-α, *P < 0.05 compared with control; $P < 0.05 compared with WY-stimulated cells. B: PPAR-γ, *P < 0.05 compared with control; $P < 0.05 compared with rosiglitazone-stimulated cells. C: RAR, *P < 0.05 compared with control.