Fig. 6.

Graphical representation of protein-protein interaction networks for hypoxia-redistributed proteins. The information on the biochemical interactions and complex formation of the 203 hypoxia-redistributed proteins were downloaded from the Saccharomyces Genome Database (SGD) database, and then imported to Cytoscape for network construction. The proteins (shown as round nodes in different colors based on their cellular functions) are placed in their respective cellular compartments in normoxic cells. The gene ontology (GO) terms for protein complexes or functional categorizations are indicated and are shown in square nodes. Nodes of the same subnetworks are colored similarly, and a key for the coloring of the nodes is shown. Lines represent an association of the protein with a particular complex or functional GO term.