Table 2.
All participants |
Never smokers | ||||
1995 | 1996 | 2001 | Combined years | Combined years | |
Adjusted† OR (95% CI) | Adjusted† OR (95% CI) | Adjusted† OR (95% CI) | Adjusted‡ OR (95% CI) | Adjusted‡ OR (95% CI) | |
n | 6278 | 6669 | 5571 | 18 518 | 7789 |
Age (years) | |||||
40–49 | 1.00 | 1.00 | 1.00 | 1.00 | 1.0 |
50–59 | 1.57 (1.22 to 2.02) | 1.25 (0.97 to 1.61) | 1.39 (1.04 to 1.87) | 1.40 (1.20 to 1.63) | 0.99 (0.73 to 1.34) |
60–69 | 2.34 (1.82 to 3.02) | 1.75 (1.35 to 2.25) | 1.74 (1.27 to 2.40) | 1.95 (1.67 to 2.28) | 1.19 (0.88 to 1.62) |
70–79 | 3.43 (2.62 to 4.48) | 2.52 (1.92 to 3.31) | 2.43 (1.75 to 3.39) | 2.80 (2.38 to 3.31) | 2.09 (1.54 to 2.84) |
80+ | 4.22 (2.93 to 6.07) | 3.52 (2.43 to 5.10) | 4.18 (2.69 to 6.50) | 3.92 (3.13 to 4.90) | 3.18 (2.20 to 4.61) |
Sex | |||||
Male | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Female | 0.79 (0.67 to 0.94) | 0.90 (0.75 to 1.08) | 0.97 (0.79 to 1.21) | 0.87 (0.78 to 0.97) | 0.97 (0.79 to 1.20) |
Smoking status | |||||
Never regular smoker | 1.00 | 1.00 | 1.00 | 1.00 | – |
Ex-regular smoker | 1.43 (1.15 to 1.78) | 1.46 (1.15 to 1.85) | 1.64 (1.25 to 2.14) | 1.50 (1.30 to 1.72) | – |
Current smoker | 3.78 (3.03 to 4.72) | 4.07 (3.23 to 5.13) | 3.99 (3.02 to 5.25) | 3.94 (3.43 to 4.52) | – |
Socioeconomic status (occupation) | |||||
Non-manual | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
Manual/other | 1.17 (0.99 to 1.39) | 1.23 (1.03 to 1.47) | 1.29 (1.05 to 1.60) | 1.22 (1.10 to 1.36) | 1.03 (0.83 to 1.27) |
Passive smoking exposure (h/week) | |||||
0 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
1–19 | 0.99 (0.82 to 1.20) | 1.13 (0.92 to 1.38) | 1.03 (0.82 to 1.30) | 1.05 (0.93 to 1.18) | 1.14 (0.91 to 1.42) |
20+ | 1.07 (0.83 to 1.39) | 1.27 (0.97 to 1.65) | 1.28 (0.91 to 1.81) | 1.18 (1.01 to 1.39) | 1.17 (0.78 to 1.76) |
Year | |||||
1995 | – | – | – | 1.0 | 1.0 |
1996 | – | – | – | 0.79 (0.70 to 0.89) | 0.75 (0.59 to 0.95) |
2001 | – | – | – | 0.70 (0.62 to 0.80) | 0.66 (0.51 to 0.85) |
Lower limit of normal (LLN) criteria24 25: participants with FEV1/FVC values >1.645 SD below the mean reference value.
Adjusted for age, sex, smoking status, socioeconomic status and passive smoking exposure.
Adjusted for age, sex, smoking status, socioeconomic status, year of study and passive smoking exposure.