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. 2011 Jul 8;301(4):L510–L518. doi: 10.1152/ajplung.00122.2011

Fig. 1.

Fig. 1.

Aged male (AM) mice have increased lung tissue volume and mortality after bleomycin (Bleo) instillation. A: lung tissue volume does not change with age, but is significantly increased in young female (YF) and male (YM) mice and AM mice after Bleo (P < 0.001). AM mice have a significant increase in lung tissue volume compared with YF and aged female (AF) (***P < 0.001) mice, and a significantly lower lung tissue volume compared with YM mice (***P < 0.001). Values are means ± SE. B: AM mice exhibit increased mortality after intratracheal administration of Bleo compared with female mice and YM mice. Sal, saline.