Table 1.
Body weight and protein concentration of 3, 12, and 24 months of control (C) and estradiol- (E2-) treated aging female rats.
| Age/treatment | Body wt. (g) | Protein content (mg/g) | ||
|---|---|---|---|---|
| Whole homogenate | Supernatant | Mitochondria | ||
| 3 months | ||||
| C | 218 ± 23 | 168 ± 17.3 | 129 ± 9.3 | 17.9 ± 1.6 |
|
| ||||
| 12 months | ||||
| C | 330 ± 18* | 160 ± 18.5 | 110 ± 4.9 | 19.5 ± 2.1 |
| E2 | 243 ± 27 | 164 ± 7.9 | 118 ± 8.6 | 20.8 ± 2.7 |
|
| ||||
| 24 months | ||||
| C | 425 ± 36$ | 156 ± 13.6 | 108 ± 7.4 | 17.2 ± 1.4 |
| E2 | 292 ± 28c | 162 ± 8.3 | 120 ± 4.5 | 18.6 ± 1.2 |
Each value is a mean ± SEM of five or more separate values from two to three experiments. The comparisons of experimental values are with the control values. Statistical significance: c P < 0.05 comparing age-matched controls versus E2 treatment and $ P < 0.001, *P < 0.05 versus 3 months.