Table 3.
Cardiometabolic biomarkers at baseline and at 10 months for the intervention and control groups with all intervention subjects included regardless of attendance at the PA sessions (unadjusted mean [SD]).
| Variable | Baseline | 10 Months | Adjusted change (SE)* | P value | ||
|---|---|---|---|---|---|---|
| Intervention | Control | Intervention | Control | |||
| Insulin, pmol/L† | 119.4 (84.8) | 101.4 (59.9) | 130.6 (79.7) | 122.4 (57.1) | −3.6 (8.9) | 0.69 |
| Glucose, mmol/L† | 4.89 (0.39) | 4.91 (0.43) | 4.85 (0.37) | 4.89 (0.38) | −0.03 (0.06) | 0.63 |
| SBP, mm Hg‡ | 104.1 (7.5) | 102.4 (9.1) | 105.1 (8.3) | 103.8 (7.6) | 0.5 (1.0) | 0.64 |
| DBP, mm Hg‡ | 59.0 (5.6) | 59.5 (5.7) | 58.3 (6.5) | 58.8 (5.4) | −0.3 (0.8) | 0.72 |
| HR, bpm‡ | 79.6 (9.2) | 79.8 (8.9) | 74.1 (8.9) | 76.9 (8.3) | −2.7 (1.1) | 0.01 |
| TC, mmol/L† | 4.18 (0.83) | 4.15 (0.70) | 4.01 (0.74) | 4.15 (0.67) | −0.15 (0.09) | 0.08 |
| TG, mmol/L† | 0.66 (0.30) | 0.63 (0.30) | 0.77 (0.37) | 0.71 (0.32) | 0.04 (0.05) | 0.46 |
| HDLC, mmol/L† | 1.34 (0.32) | 1.29 (0.28) | 1.36 (0.31) | 1.34 (0.31) | −0.01 (0.04) | 0.73 |
| LDLC, mmol/L† | 2.67 (0.85) | 2.67 (0.69) | 2.47 (0.70) | 2.67 (0.75) | −0.20 (0.10) | 0.04 |
| LP(a), mg/dL† | 45.5 (30.1) | 50.6 (42.8) | 47.8 (31.1) | 57.3 (48.1) | −4.48 (3.59) | 0.21 |
| LDL size, nm† | 26.1 (0.69) | 26.2 (0.69) | 25.7 (0.82) | 25.8 (0.72) | −0.09 (0.14) | 0.50 |
| %HDL2 † | 36.9 (20.3) | 36.7 (20.2) | 36.1 (20.3) | 35.8 (17.6) | 0.17 (3.30) | 0.96 |
| ApoA1, mg/dL† | 132.8 (32.3) | 124.3 (22.7) | 126.2 (22.1) | 125.3 (20.7) | −1.31 (3.68) | 0.72 |
| ApoB, mg/dL† | 77.6 (29.9) | 77.3 (26.1) | 71.9 (26.6) | 74.1 (21.9) | −2.3 (4.3) | 0.60 |
| ApoCIII, ng/mL† | 12.0 (3.8) | 11.4 (3.9) | 11.1 (4.2) | 11.5 (4.3) | −0.62 (0.69) | 0.37 |
| ApoE, ng/mL† | 5.26 (1.49) | 5.03 (1.75) | 5.04 (1.56) | 4.78 (1.56) | 0.09 (0.20) | 0.66 |
| CRP, ng/mL† | 757.3 (1571.0) | 694.2 (883.6) | 597.9 (1333.7) | 795.8 (1120.5) | −245.8 (145.2) | 0.09 |
| Fibrinogen, mg/dL† | 2.72 (0.51) | 2.77 (0.55) | 2.89 (0.50) | 2.91 (0.60) | 0.02 (0.08) | 0.83 |
SD: standard deviation; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; TC: total cholesterol; TG: triglycerides; HDLC: high-density lipoprotein cholesterol; LDLC: low-density lipoprotein cholesterol; Lp(a): lipoprotein(a); VLDL: very low-density lipoprotein; Apo: apolipoprotein; CRP: C-reactive protein.
*Change estimates and standard errors (SE) are the differences between intervention and control groups adjusted for age and baseline value.
†Intervention N = 74, Control N = 60.
‡Intervention N = 118, Control N = 82.