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The increase in 8-isoprostaglandin F2α in muscle interstitial fluid during contraction before (filled bars) and after 200 mg/kg tempol intra-venous injection (open bars) in rats whose hindlimbs are freely perfused and whose femoral artery had been ligated 72 h prior. Baseline 8-isoprostaglandin F2α concentrations are within vertical bars. Means ± SE. *Significant difference (P < 0.05) between baseline and peak.
