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. 2011 Jul 7;111(4):971–979. doi: 10.1152/japplphysiol.00535.2011

Table 2.

Baseline and peak responses in MAP, HR, and TTI for static contraction in rats whose hindlimbs were freely perfused and in rats whose femoral artery had been ligated 72 h before the start of the experiment before and after intravenous tempol injection

MAP, mmHg
HR, beats/min
n Baseline Peak Δ Baseline Peak Δ TTI, kg · s
Freely perfused group
Control 6 85 ± 4 102 ± 5* 17 ± 2 414 ± 18 433 ± 17* 19 ± 3 21.8 ± 2.5
Tempol (10 mg iv) 6 77 ± 5 93 ± 7* 16 ± 2 388 ± 14 409 ± 14* 21 ± 4 22.8 ± 2.4
Ligated (72 h) group
Control 6 92 ± 5 129 ± 11* 37 ± 7 396 ± 17 424 ± 13* 27 ± 8 19.8 ± 1.7
Tempol (10 mg iv) 6 95 ± 4 131 ± 6* 36 ± 5 348 ± 55 368 ± 56* 20 ± 5 18.5 ± 1.6

Values are means ± SE, n, no. of rats. MAP, mean arterial pressure; HR, heart rate.

*

P < 0.05, peak vs. baseline;

P < 0.05, 72 h ligated vs. freely perfused.