Table 2.
MAP, mmHg |
HR, beats/min |
|||||||
---|---|---|---|---|---|---|---|---|
n | Baseline | Peak | Δ | Baseline | Peak | Δ | TTI, kg · s | |
Freely perfused group | ||||||||
Control | 6 | 85 ± 4 | 102 ± 5* | 17 ± 2 | 414 ± 18 | 433 ± 17* | 19 ± 3 | 21.8 ± 2.5 |
Tempol (10 mg iv) | 6 | 77 ± 5 | 93 ± 7* | 16 ± 2 | 388 ± 14 | 409 ± 14* | 21 ± 4 | 22.8 ± 2.4 |
Ligated (72 h) group | ||||||||
Control | 6 | 92 ± 5 | 129 ± 11* | 37 ± 7† | 396 ± 17 | 424 ± 13* | 27 ± 8 | 19.8 ± 1.7 |
Tempol (10 mg iv) | 6 | 95 ± 4 | 131 ± 6* | 36 ± 5† | 348 ± 55 | 368 ± 56* | 20 ± 5 | 18.5 ± 1.6 |
Values are means ± SE, n, no. of rats. MAP, mean arterial pressure; HR, heart rate.
P < 0.05, peak vs. baseline;
P < 0.05, 72 h ligated vs. freely perfused.