Table 1.

Plasma and urine electrolytes with K⁺ depletion

	Control	Hypokalemia
Plasma Na+	138 ± 1.7 (5)	141 ± 3.8 (5)
Plasma K+	4.6 ± 0.2 (5)	2.8 ± 0.2 (5)*
pH	7.37 ± 0.01 (5)	7.42 ± 0.02*
HCO3−	24.9 ± 1.9 (5)	28.6 ± 1.4 (5)*
Pco2	40.6 ± 1.9 (5)	40.5 ± 1.6
Urine volume, ml/day	14.4 ± 1.6 (7)	22.6 ± 4.9 (8)
Urine osmolality, mosmol/kgH2O	1,756 ± 387 (7)	767 ± 305 (8)*
Urine ammonia concentration, mmol/l	24.9 ± 6.6 (5)	171.5 ± 51.8 (8)*
Urine ammonia content, mmol/day	0.39 ± 0.16 (10)	2.77 ± 0.41 (12)*
Urine pH	6.83 ± 0.13 (5)	7.60 ± 0.28 (5)*

Values are means ± SE. Numbers in parentheses indicate number of animals studied.

^*P < 0.05.