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. 2011 Jul 27;106(4):2057–2064. doi: 10.1152/jn.00450.2011

Fig. 1.

Fig. 1.

Nanomolar 4,5,6,7-tetrahydroisoxazolo (5,4-c)pyridin-3(-ol) (THIP) currents are observed in cerebellar granule cells (CGCs) but not molecular layer interneurons (MLIs). A and C: currents elicited by the indicated concentrations of THIP in a granule cell and in a MLI. Note that 1 μM THIP evokes a >50-pA current from the granule cell but is ineffective on the interneuron. GBZ, gabazine. B and D: summary histograms indicating mean concentration dependence of THIP currents in granule cells and in MLIs. Numbers above bars indicate n values; *significant current compared with sham perfusion (P < 0.005).