Table 2. Levels of Long-Term Follow-Up Care^‡ for Childhood Cancer Survivors.

Risk of Late Effects	Proposed Levels of Follow-Up Care
Low Surgery only; low-risk chemotherapy (excluding alkylators, anthracyclines, bleomycin, epipodophyllotoxins)	Postal or telephone follow-up every 1 to 2 years Single visit with cancer center long-term follow-up program followed by ongoing monitoring by primary care provider, according to follow-up plan established by cancer center
Moderate Other than high/low risk	Follow-up every 1 to 2 years with nurse or primary care physician Initial follow-up at cancer center for 5-10 years, followed by transition to primary care provider, who performs ongoing monitoring according to follow-up plan established by cancer center
High Hematopoietic cell transplant; high-dose anthracyclines or alkylating agents; radiation ≥24 Gy	Ongoing annual follow-up in specialized long-term follow-up program at cancer center

^‡Long-term follow-up begins 2 years following completion of therapy

Adapted from references ^27-31