Table 4.
Clinical success at TOC by diagnosis (PP and ITT populations), as assessed by the DRC
| Clinical cure, n/N (%) |
||||||
|---|---|---|---|---|---|---|
| PP |
ITT |
|||||
| moxifloxacin (N = 361) | TZP–AMC (N = 307) | estimate: 95% CI | moxifloxacin (N = 426) | TZP–AMC (N = 377) | estimate: 95% CI | |
| All patients | 320/361 (88.6) | 275/307 (89.6) | −0.72: −5.3, 3.9 | 350/426 (82.2) | 305/377 (80.9) | 1.25: −3.8, 6.3 |
| Diagnosis | ||||||
| major abscess | 160/167 (95.8) | 147/153 (96.1) | 0.2: −4.2, 4.5 | 163/183 (89.1) | 151/169 (89.3) | 0.8: −5.6, 7.2 |
| diabetic foot infection | 84/110 (76.4) | 75/96 (78.1) | −2.8: −14.5, 9.0 | 86/123 (69.9) | 76/110 (69.1) | −0.1: −12.4, 12.1 |
| wound infection | 59/62 (95.2) | 45/47 (95.7) | −1.4: −9.7, 6.8 | 65/72 (90.3) | 48/55 (87.3) | 2.3: −8.6, 13.2 |
| infected ischaemic ulcer | 17/22 (77.3) | 8/11 (72.7) | 6.2: −27.2, 39.6 | 17/24 (70.8) | 9/18 (50.0) | 20.1: −9.0, 49.2 |
n/N, number of patients experiencing clinical cure/number of patients with a given diagnosis.