Figure 7.

Kinetic differences between HSV-2 shedding episodes in persons on and off the study drug. (a) Episodes of 4 day duration (15 episodes off and 9 episodes on the drug) generated from median (continuous lines) as well as 5th and 95th percentile (broken lines) HSV DNA quantities obtained at each timepoint; first and peak genomic copy numbers were lower in persons on the drug, while last positive copy number was equivalent in the two groups. (b) Episodes of median duration (36 5 day episodes off the study drug and 25 2 day episodes on the drug) generated from median (continuous lines) as well as 5th and 95th percentile (broken lines) HSV DNA quantities obtained at each timepoint; peak genomic copy number was lower in persons on the drug, while the first and last positive copy numbers were equivalent in the two groups.