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. 2011 Jul;79(7):2801–2809. doi: 10.1128/IAI.00203-11

Fig. 2.

Fig. 2.

Placental malaria does not alter the Treg/Teff cell ratio in neonates. (A) Ratio of the frequencies of regulatory CD4+ CD25+ CD127−,low Foxp3+ cells to effector CD4+ CD25+ CD127+ Foxp3− cells in neonates according to mother's parity and PM (n = 10 for PMneg and n = 13 for PMpos primigravid women; n = 15 for PMneg and n = 14 for PMpos multigravid women). Individual (symbols) and median (bars) values are shown. (B) Correlation between frequencies of Treg and Teff cells in neonates from PM-negative mothers (left panel, n = 25) and PM-positive mothers (right panel, n = 26). (C) Treg/Teff cell ratio according to placental parasitemia (left panel, n = 26) and P. falciparum-induced placental inflammation (defined as the number of monocytes containing malarial pigment) (right panel, n = 26). P and Rho values were determined with the Spearman correlation test.