Fig. 4.
The presence of P. falciparum-induced CD25high CD4+ T cells among CBMC correlates with the highest IL-6, IL-10, and TNF-α responses to live parasites. Frequencies of P. falciparum-induced CD25high CD4+ T cells determined after 40 h of in vitro culture with live parasites were plotted against IL-6 (n = 16), IL-10 (n = 17), and TNF-α (n = 20) concentrations (iRBC-uRBC) measured in supernatants. Empty circles, neonates from PM-negative mothers; filled circles, neonates from PM-positive mothers; triangles, healthy Beninese adults.