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Induction of relapse by vancomycin treatment. (A) Experimental scheme. Group 1 mice (n = 10) were orally administered vancomycin for 9 consecutive days starting on day 2 after C. difficile challenge; group 2 received the same treatment as group 1 plus a C. difficile rechallenge on day 11 (after withdraw of vancomycin treatment). Data on the diarrhea (B), survival (C), and weight loss (D) of the two groups of mice are shown.
