Skip to main content
. 2011 Jul;79(7):2586–2596. doi: 10.1128/IAI.00920-10

Fig. 2.

Fig. 2.

TLR2−/− mice exhibit an increased parasite burden. WT and TLR2−/− were i.c. infected with ∼40 M. corti metacestodes. At 1 week (wk) and 3 weeks p.i., WT and TLR2−/− mice were sacrificed. The location and number of parasites were determined by microscopic examination of serial H&E-stained brain sections. (A) Total numbers of parasites present in the brains of WT and TLR2−/− mice. Significant differences in parasite numbers in M. corti-infected TLR2−/− compared with the infected WT animals is denoted by an asterisk (P < 0.05). (B) Percentages of parasites present in parenchymal (P) and extraparenchymal (EP) regions in individual brains were calculated. Results are from three independent experiments. Significant differences in parasite numbers in M. corti-infected TLR2−/− compared with the infected WT animals are indicated (*, P < 0.05; **, P < 0.005).