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. 2011 Jul;79(7):2699–2708. doi: 10.1128/IAI.00079-11

Fig. 2.

Fig. 2.

In vitro-activated NK cells readily kill YAC-1 tumor targets but are not cytotoxic against uninfected or infected B6 BM-Mφ. NK cells from the spleens of RAG1−/− mice were stimulated for 18 h with rmIL-12 plus rmIL-18 and used as effector cells in 4-h (A) and 18-h (B) chromium-51 release assays. The mean (±SEM) of three independent experiments is shown as percent specific lysis against uninfected and L. infantum-infected BM-Mφ (parasite/cell ratio = 10:1) or YAC-1 tumor cells.