Fig. 1.

Akt2 activation controls host survival to S. Typhimurium infection. WT mice and mice lacking Akt2 were treated with streptomycin prior to infection with S. Typhimurium and monitored for signs of morbidity and mortality. The percent survival in Akt2 KO mice and WT mice is shown. P values for survival curves of KO mice compared to those of WT mice were determined using the log rank test. Data are representative of two independent experiments with a total of at least 15 mice from each group.